Research Library
The following research library is for informational use only. Curated Wellness provides this information as a service and does not receive compensation for studies referenced. This information should not be read to recommend or endorse any specific products. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease.
Select a curation to learn more about the published research we use to better understand nutrients and their roles.
Curations
1. Holscher H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut microbes, 8(2), 172–184. https://doi.org/10.1080/19490976.2017.1290756
2. Vighi, et al. (2008). Allergy and the gastrointestinal system. Clinical and Experimental Immunology. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515351/
3. McMullen, M. K., Whitehouse, J. M., & Towell, A. (2015). Bitters: Time for a New Paradigm. Evidence-based complementary and alternative medicine : eCAM, 2015, 670504. https://doi.org/10.1155/2015/670504
4. Ouwehand, Arthur, “Antiallergic effects of probiotics,” Journal of Nutrition, Mar 2007
5. Shi, L. H., Balakrishnan, K., Thiagarajah, K., Mohd Ismail, N. I., & Yin, O. S. (2016). Beneficial Properties of Probiotics. Tropical life sciences research, 27(2), 73–90. https://doi.org/10.21315/tlsr2016.27.2.6
6. Rao, R., & Samak, G. (2012). Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions. Journal of epithelial biology & pharmacology, 5(Suppl 1-M7), 47–54. https://doi.org/10.2174/1875044301205010047
7. Ianiro, G., Pecere, S., Giorgio, V., Gasbarrini, A., & Cammarota, G. (2016). Digestive Enzyme Supplementation in Gastrointestinal Diseases. Current drug metabolism, 17(2), 187–193. https://doi.org/10.2174/138920021702160114150137
8. Money ME, Walkowiak J, Virgilio C, et al. Pilot study: a randomised, double blind, placebo controlled trial of pancrealipase for the treatment of postprandial irritable bowel syndrome-diarrhoea. Frontline Gastroenterol. 2011;2:48-56. doi:10.1136/fg.2010.002253
1.https://www.clinicaleducation.org/resources/reviews/the-role-of-hcl-in-gastric-function-and-health/
2. Brugger, D., & Windisch, W. M. (2016). Subclinical zinc deficiency impairs pancreatic digestive enzyme activity and digestive capacity of weaned piglets. The British journal of nutrition, 116(3), 425–433. https://doi.org/10.1017/S0007114516002105
3. McMullen, M. K., Whitehouse, J. M., & Towell, A. (2015). Bitters: Time for a New Paradigm. Evidence-based complementary and alternative medicine : eCAM, 2015, 670504. https://doi.org/10.1155/2015/670504
4.https://www.sciencedaily.com/releases/2016/06/160609115127.htm
5. Holscher H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut microbes, 8(2), 172–184. https://doi.org/10.1080/19490976.2017.1290756
6. Money ME, Walkowiak J, Virgilio C, et al. Pilot study: a randomised, double blind, placebo controlled trial of pancrealipase for the treatment of postprandial irritable bowel syndrome-diarrhoea. Frontline Gastroenterol. 2011;2:48-56. doi:10.1136/fg.2010.002253
7. Shi, L. H., Balakrishnan, K., Thiagarajah, K., Mohd Ismail, N. I., & Yin, O. S. (2016). Beneficial Properties of Probiotics. Tropical life sciences research, 27(2), 73–90. https://doi.org/10
1. McMullen, M. K., Whitehouse, J. M., & Towell, A. (2015). Bitters: Time for a New Paradigm. Evidence-based complementary and alternative medicine : eCAM, 2015, 670504. https://doi.org/10.1155/2015/670504
2. Holscher H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut microbes, 8(2), 172–184. https://doi.org/10.1080/19490976.2017.1290756
3. Ouwehand, Arthur, “Antiallergic effects of probiotics,” Journal of Nutrition, Mar 2007
4. Shi, L. H., Balakrishnan, K., Thiagarajah, K., Mohd Ismail, N. I., & Yin, O. S. (2016). Beneficial Properties of Probiotics. Tropical life sciences research, 27(2), 73–90. https://doi.org/10.21315/tlsr2016.27.2.6
5. Pituch, A., Walkowiak, J., & Banaszkiewicz, A. (2013). Butyric acid in functional constipation. Przeglad gastroenterologiczny, 8(5), 295–298. https://doi.org/10.5114/pg.2013.38731
6. Banasiewicz, T., Krokowicz, Ł., Stojcev, Z., Kaczmarek, B. F., Kaczmarek, E., Maik, J., Marciniak, R., Krokowicz, P., Walkowiak, J., & Drews, M. (2013). Microencapsulated sodium butyrate reduces the frequency of abdominal pain in patients with irritable bowel syndrome. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 15(2
1. Shi, L. H., Balakrishnan, K., Thiagarajah, K., Mohd Ismail, N. I., & Yin, O. S. (2016). Beneficial Properties of Probiotics. Tropical life sciences research, 27(2), 73–90. https://doi.org/10.21315/tlsr2016.27.2.6
2. McMullen, M. K., Whitehouse, J. M., & Towell, A. (2015). Bitters: Time for a New Paradigm. Evidence-based complementary and alternative medicine : eCAM, 2015, 670504. https://doi.org/10.1155/2015/670504
3. Holscher H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut microbes, 8(2), 172–184. https://doi.org/10.1080/19490976.2017.1290756
4. Villarreal, J., Kahn, C. A., Dunford, J. V., Patel, E., & Clark, R. F. (2015). A retrospective review of the prehospital use of activated charcoal. The American journal of emergency medicine, 33(1), 56–59. https://doi.org/10.1016/j.ajem.2014.10.019
5. Money ME, Walkowiak J, Virgilio C, et al. Pilot study: a randomised, double blind, placebo controlled trial of pancrealipase for the treatment of postprandial irritable bowel syndrome-diarrhoea. Frontline Gastroenterol. 2011;2:48-56. doi:10.1136/fg.2010.002253
2.https://pubmed.ncbi.nlm.nih.gov/21784145/
3.https://www.healthline.com/nutrition/17-health-benefits-of-omega-3#TOC_TITLE_HDR_2
4.https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/#h2
5.https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
6. Kennedy D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients, 8(2), 68. https://doi.org/10.3390/nu8020068
7. Young, L. M., Pipingas, A., White, D. J., Gauci, S., & Scholey, A. (2019). A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and 'At-Risk' Individuals. Nutrients, 11(9), 2232. https://doi.org/10.3390/nu11092232
8. Smith, S. M., & Vale, W. W. (2006). The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues in clinical neuroscience, 8(4), 383–395. https://doi.org/10.31887/DCNS.2006.8.4/ssmith
9. Hooper, M.H., Carr, A. & Marik, P.E. The adrenal-vitamin C axis: from fish to guinea pigs and primates. Crit Care 23, 29 (2019). https://doi.org/10.1186/s13054-019-2332-x
10. Wilson, J. L. (2017). Adrenal fatigue: The 21st century stress syndrome. Petaluma, CA: Smart Publications.
11. Yu-Yahiro J. A. (1994). Electrolytes and their relationship to normal and abnormal muscle function. Orthopedic nursing, 13(5), 38–40. https://doi.org/10.1097/00006416-199409000-00008
12. Hew-Butler, T., Loi, V., Pani, A., & Rosner, M. H. (2017). Exercise-Associated Hyponatremia: 2017 Update. Frontiers in medicine, 4, 21. https://doi.org/10.3389/fmed.2017.00021
2.https://pubmed.ncbi.nlm.nih.gov/21784145/
3.https://www.healthline.com/nutrition/17-health-benefits-of-omega-3#TOC_TITLE_HDR_2
4.https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/#h2
5.https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
6. Kennedy D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients, 8(2), 68. https://doi.org/10.3390/nu8020068
7. Young, L. M., Pipingas, A., White, D. J., Gauci, S., & Scholey, A. (2019). A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and 'At-Risk' Individuals. Nutrients, 11(9), 2232. https://doi.org/10.3390/nu11092232
8. Anderson, J. W., Baird, P., Davis, R. H., Jr, Ferreri, S., Knudtson, M., Koraym, A., Waters, V., & Williams, C. L. (2009). Health benefits of dietary fiber. Nutrition reviews, 67(4), 188–205. https://doi.org/10.1111/j.1753-4887.2009.00189.x
9. Weickert, M. O., & Pfeiffer, A. F. (2008). Metabolic effects of dietary fiber consumption and prevention of diabetes. The Journal of nutrition, 138(3), 439–442. https://doi.org/10.1093/jn/138.3.439
2.https://pubmed.ncbi.nlm.nih.gov/21784145/
3.https://www.healthline.com/nutrition/17-health-benefits-of-omega-3#TOC_TITLE_HDR_2
4.https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/#h2
5.https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
6. Kennedy D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients, 8(2), 68. https://doi.org/10.3390/nu8020068
7. Young, L. M., Pipingas, A., White, D. J., Gauci, S., & Scholey, A. (2019). A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and 'At-Risk' Individuals. Nutrients, 11(9), 2232. https://doi.org/10.3390/nu11092232
8. Hooper, M.H., Carr, A. & Marik, P.E. The adrenal-vitamin C axis: from fish to guinea pigs and primates. Crit Care 23, 29 (2019). https://doi.org/10.1186/s13054-019-2332-x
10. Sartori SB, et al. (2012). Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment. DOI: 10.1016/j.neuropharm.2011.07.027
11. Kirkland, A. E., Sarlo, G. L., & Holton, K. F. (2018). The Role of Magnesium in Neurological Disorders. Nutrients, 10(6), 730. https://doi.org/10.3390/nu10060730
12. Reddy, P., & Edwards, L. R. (2019). Magnesium Supplementation in Vitamin D Deficiency. American journal of therapeutics, 26(1), e124–e132. https://doi.org/10.1097/MJT.0000000000000538
1. Anderson, J. W., Baird, P., Davis, R. H., Jr, Ferreri, S., Knudtson, M., Koraym, A., Waters, V., & Williams, C. L. (2009). Health benefits of dietary fiber. Nutrition reviews, 67(4), 188–205. https://doi.org/10.1111/j.1753-4887.2009.00189.x
2. Clifford, T., Howatson, G., West, D. J., & Stevenson, E. J. (2015). The potential benefits of red beetroot supplementation in health and disease. Nutrients, 7(4), 2801–2822. https://doi.org/10.3390/nu7042801
3. Morisco, F., Lembo, V., Mazzone, G., Camera, S., & Caporaso, N. (2014). Coffee and liver health. Journal of clinical gastroenterology, 48 Suppl 1, S87–S90. https://doi.org/10.1097/MCG.0000000000000240
4. Trefts, E., Gannon, M., & Wasserman, D. H. (2017). The liver. Current biology : CB, 27(21), R1147–R1151. https://doi.org/10.1016/j.cub.2017.09.019
5.https://www.atherosclerosis-journal.com/article/S0021-9150(10)00595-2/fulltext
6.https://www.sciencedirect.com/science/article/abs/pii/S1388198111001120
7. Ripps, H., & Shen, W. (2012). Review: taurine: a "very essential" amino acid. Molecular vision, 18, 2673–2686.
8. Liu, M., Yang, H., & Mao, Y. (2019). Magnesium and liver disease. Annals of translational medicine, 7(20), 578. https://doi.org/10.21037/atm.2019.09.70
9.https://aasld.confex.com/aasld/2020/meetingapp.cgi/Paper/21865
10. Honda, Y., Kessoku, T., Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Tomeno, W., Imajo, K., Fujita, K., Yoneda, M., Kataoka, K., Taguri, M., Yamanaka, T., Seko, Y., Tanaka, S., Saito, S., Ono, M., Oeda, S., Eguchi, Y., Aoi, W., … Nakajima, A. (2017). Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. BMC gastroenterology, 17(1), 96. https://doi.org/10.1186/s12876-017-0652-3
1. Marttinen, M., Ala-Jaakkola, R., Laitila, A., & Lehtinen, M. J. (2020). Gut Microbiota, Probiotics and Physical Performance in Athletes and Physically Active Individuals. Nutrients, 12(10), 2936. https://doi.org/10.3390/nu12102936
2. Shuler, F. D., Wingate, M. K., Moore, G. H., & Giangarra, C. (2012). Sports health benefits of vitamin d. Sports health, 4(6), 496–501. https://doi.org/10.1177/1941738112461621
3. Marawan A, Kurbanova N, Qayyum R. Association between serum vitamin D levels and cardiorespiratory fitness in the adult population of the USA. European Journal of Preventive Cardiology. 2019;26(7):750-755. doi:1177/2047487318807279
4. McFarlin, B. K., Henning, A. L., & Venable, A. S. (2017). Oral Consumption of Vitamin K2 for 8 Weeks Associated With Increased Maximal Cardiac Output During Exercise. Alternative therapies in health and medicine, 23(4), 26–32.
5. Lewis, E.J.H., Radonic, P.W., Wolever, T.M.S., & Wells, G.D. (2015). 21 days of mammalian omega-3 fatty acid supplementation improves aspects of neuromuscular function and performance in male athletes compared to olive oil placebo. Journal of the International Society of Sports Nutrition, 12(28). doi: 10.1186/s12970-015-0089-4
6. Da Boit, M., Hunter, A.M., & Gray, S.R. (2017). Fit with good fat? The role of n-3 polyunsaturated fatty acids on exercise performance. Metabolism, 66, 45-54. doi: 10.1016/j.metabol.2016.10.007
7. Price, C. T., Langford, J. R., & Liporace, F. A. (2012). Essential Nutrients for Bone Health and a Review of their Availability in the Average North American Diet. The open orthopaedics journal, 6, 143–149. https://doi.org/10.2174/1874325001206010143
8.https://americanbonehealth.org/nutrition/minerals-for-bone-health/
1. Carr, A. C., & Maggini, S. (2017). Vitamin C and Immune Function. Nutrients, 9(11), 1211. https://doi.org/10.3390/nu9111211
2.https://www.karger.com/Article/FullText/496426
3. La Fata G, Weber P, Mohajeri MH. Probiotics and the gut immune system: indirect regulation. Probiotics Antimicrob Proteins. 2018;10(1):11-21.
4. Aziz N, Bonavida B. Activation of natural killer cells by probiotics. For Immunopathol Dis Therap. 2016;7(1-2):41-55.
5. NAC - Research on Glutothione: Gaucher C, Boudier A, Bonetti J. Glutathione: Antioxidant Properties Dedicated to Nanotechnologies. Antioxidants (Basel). 2018 May;7(5):62. doi:10.3390/antiox7050062.
6. Atkuri, K. R., Mantovani, J. J., Herzenberg, L. A., & Herzenberg, L. A. (2007). N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency. Current opinion in pharmacology, 7(4), 355–359. https://doi.org/10.1016/j.coph.2007.04.005
7. Steinbrenner, H., Al-Quraishy, S., Dkhil, M. A., Wunderlich, F., & Sies, H. (2015). Dietary selenium in adjuvant therapy of viral and bacterial infections. Advances in nutrition (Bethesda, Md.), 6(1), 73–82. https://doi.org/10.3945/an.114.007575
8. Huang, Z., Rose, A. H., & Hoffmann, P. R. (2012). The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities. Antioxidants & redox signaling, 16(7), 705–743. https://doi.org/10.1089/ars.2011.4145
9. Hemilä H. (2017). Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. JRSM open, 8(5), 2054270417694291. https://doi.org/10.1177/2054270417694291
10. Haase, H., & Rink, L. (2009). The immune system and the impact of zinc during aging. Immunity & ageing : I & A, 6, 9. https://doi.org/10.1186/1742-4933-6-9
11. Huang, Z., Liu, Y., Qi, G., Brand, D., & Zheng, S. G. (2018). Role of Vitamin A in the Immune System. Journal of clinical medicine, 7(9), 258. https://doi.org/10.3390/jcm7090258
12. Lewis, E. D., Meydani, S. N., & Wu, D. (2019). Regulatory role of vitamin E in the immune system and inflammation. IUBMB life, 71(4), 487–494. https://doi.org/10.1002/iub.1976
13. Martens, P. J., Gysemans, C., Verstuyf, A., & Mathieu, A. C. (2020). Vitamin D's Effect on Immune Function. Nutrients, 12(5), 1248. https://doi.org/10.3390/nu12051
1. Frontiers | The Anti-Inflammatory Role of Omega-3 Polyunsaturated Fatty Acids Metabolites in Pre-Clinical Models of Psychiatric, Neurodegenerative, and Neurological Disorders | Psychiatry (frontiersin.org)
2. Sharifi-Rad, J., Rayess, Y. E., Rizk, A. A., Sadaka, C., Zgheib, R., Zam, W., Sestito, S., Rapposelli, S., Neffe-Skocińska, K., Zielińska, D., Salehi, B., Setzer, W. N., Dosoky, N. S., Taheri, Y., El Beyrouthy, M., Martorell, M., Ostrander, E. A., Suleria, H., Cho, W. C., Maroyi, A., … Martins, N. (2020). Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications. Frontiers in pharmacology, 11, 01021. https://doi.org/10.3389/fphar.2020.01021
3. McCarty, M. F., O'Keefe, J. H., & DiNicolantonio, J. J. (2018). Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection. The Ochsner journal, 18(1), 81–87.
4.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054728/
5. Liu, L., Lu, Y., Bi, X. et al. Choline ameliorates cardiovascular damage by improving vagal activity and inhibiting the inflammatory response in spontaneously hypertensive rats. Sci Rep 7, 42553 (2017). https://doi.org/10.1038/srep42553
1. Mirza, F. G., Abdul-Kadir, R., Breymann, C., Fraser, I. S., & Taher, A. (2018). Impact and management of iron deficiency and iron deficiency anemia in women's health. Expert review of hematology, 11(9), 727–736. https://doi.org/10.1080/17474086.2018.1502081
2.https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/#h2
3. Bohon, T. M., & Goolsby, M. A. (2013). The Role of Vitamin D Supplements in Women's Health. Clinical medicine insights. Women's health, 6, 67–70. https://doi.org/10.4137/CMWH.S11067
4.https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
5. Clifford, T., Howatson, G., West, D. J., & Stevenson, E. J. (2015). The potential benefits of red beetroot supplementation in health and disease. Nutrients, 7(4), 2801–2822. https://doi.org/10.3390/nu7042801
6. Kiecolt-Glaser, J. K., Belury, M. A., Andridge, R., Malarkey, W. B., & Glaser, R. (2011). Omega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial. Brain, behavior, and immunity, 25(8), 1725–1734. https://doi.org/10.1016/j.bbi.2011.07.229
7. Sergeant, S., Rahbar, E., & Chilton, F. H. (2016). Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. European journal of pharmacology, 785, 77–86. https://doi.org/10.1016/j.ejphar.2016.04.020
8. Walker, A. F., De Souza, M. C., Vickers, M. F., Abeyasekera, S., Collins, M. L., & Trinca, L. A. (1998). Magnesium supplementation alleviates premenstrual symptoms of fluid retention. Journal of women's health, 7(9), 1157–1165. https://doi.org/10.1089/jwh.1998.7.1157
1. Bello, A. E., & Oesser, S. (2006). Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature. Current medical research and opinion, 22(11), 2221–2232. https://doi.org/10.1185/030079906X148373
2. Yu, Y., Dunaway, S., Champer, J., Kim, J., & Alikhan, A. (2020). Changing our microbiome: probiotics in dermatology. The British journal of dermatology, 182(1), 39–46. https://doi.org/10.1111/bjd.18088
3. Michael I McBurney, Nathan L Tintle, Ramachandran S Vasan, Aleix Sala-Vila, William S Harris, Using an erythrocyte fatty acid fingerprint to predict risk of all-cause mortality: the Framingham Offspring Cohort, The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1447–1454, https://doi.org/10.1093/ajcn/nqab195
4. Molfino, A., Gioia, G., Rossi Fanelli, F., & Muscaritoli, M. (2014). The role for dietary omega-3 fatty acids supplementation in older adults. Nutrients, 6(10), 4058–4073. https://doi.org/10.3390/nu6104058
5.https://juniperpublishers.com/ctbeb/pdf/CTBEB.MS.ID.555716.pdf
6. Mikkelsen, K., & Apostolopoulos, V. (2018). B Vitamins and Ageing. Sub-cellular biochemistry, 90, 451–470. https://doi.org/10.1007/978-981-13-2835-0_15
7. Cabrera Á. J. (2015). Zinc, aging, and immunosenescence: an overview. Pathobiology of aging & age related diseases, 5, 25592. https://doi.org/10.3402/pba.v5.25592
8. Cui, H., Kong, Y., & Zhang, H. (2012). Oxidative stress, mitochondrial dysfunction, and aging. Journal of signal transduction, 2012, 646354. https://doi.org/10.1155/2012/646354
9.https://www.researchgate.net/publication/329378691_Selenium_aging_and_aging-related_diseases
1.https://www.sciencedirect.com/science/article/abs/pii/S0197458013003357
2. Chung, S. Y., Moriyama, T., Uezu, E., Uezu, K., Hirata, R., Yohena, N., Masuda, Y., Kokubu, T., & Yamamoto, S. (1995). Administration of phosphatidylcholine increases brain acetylcholine concentration and improves memory in mice with dementia. The Journal of nutrition, 125(6), 1484–1489. https://pubmed.ncbi.nlm.nih.gov/7782901/
3. Shults, C. W., Oakes, D., Kieburtz, K., Beal, M. F., Haas, R., Plumb, S., Juncos, J. L., Nutt, J., Shoulson, I., Carter, J., Kompoliti, K., Perlmutter, J. S., Reich, S., Stern, M., Watts, R. L., Kurlan, R., Molho, E., Harrison, M., Lew, M., & Parkinson Study Group (2002). Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline. Archives of neurology, 59(10), 1541–1550. https://doi.org/10.1001/archneur.59.10.1541
4.https://www.frontiersin.org/articles/10.3389/fnagi.2019.00103/full
5. Mohajeri, M. H., Troesch, B., & Weber, P. (2015). Inadequate supply of vitamins and DHA in the elderly: implications for brain aging and Alzheimer-type dementia. Nutrition (Burbank, Los Angeles County, Calif.), 31(2), 261–275. https://doi.org/10.1016/j.nut.2014.06.016
6.https://www.tandfonline.com/doi/abs/10.1080/00048670701827275
7. Kirkland, A. E., Sarlo, G. L., & Holton, K. F. (2018). The Role of Magnesium in Neurological Disorders. Nutrients, 10(6), 730. https://doi.org/10.3390/nu10060730
8. Slutsky I, Abumaria N, Wu LJ, et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010;65(2):165-177.
9. Krikorian, R., Eliassen, J. C., Boespflug, E. L., Nash, T. A., & Shidler, M. D. (2010). Improved cognitive-cerebral function in older adults with chromium supplementation. Nutritional neuroscience, 13(3), 116–122. https://doi.org/10.1179/147683010X12611460764084
2. Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47–55. https://doi.org/10.1159/000351376
3. Ghee: Canani, R. B., Costanzo, M. D., Leone, L., Pedata, M., Meli, R., & Calignano, A. (2011). Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World journal of gastroenterology, 17(12), 1519–1528. https://doi.org/10.3748/wjg.v17.i12.1519
4.https://www.healthline.com/nutrition/ghee#Benefits-of-ghee
5. Chacko, S. M., Thambi, P. T., Kuttan, R., & Nishigaki, I. (2010). Beneficial effects of green tea: a literature review. Chinese medicine, 5, 13. https://doi.org/10.1186/1749-8546-5-13
6. House, J. D., Neufeld, J., & Leson, G. (2010). Evaluating the quality of protein from hemp seed (Cannabis sativa L.) products through the use of the protein digestibility-corrected amino acid score method. Journal of agricultural and food chemistry, 58(22), 11801–11807. https://doi.org/10.1021/jf102636b
7. Zaineddin, A. K., Buck, K., Vrieling, A., Heinz, J., Flesch-Janys, D., Linseisen, J., & Chang-Claude, J. (2012). The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study. Nutrition and cancer, 64(5), 652–665. https://doi.org/10.1080/01635581.2012.683227
8. Phillips, K. M., Ruggio, D. M., & Ashraf-Khorassani, M. (2005). Phytosterol composition of nuts and seeds commonly consumed in the United States. Journal of agricultural and food chemistry, 53(24), 9436–9445. https://doi.org/10.1021/jf051505h
9. Clifford, T., Howatson, G., West, D. J., & Stevenson, E. J. (2015). The potential benefits of red beetroot supplementation in health and disease. Nutrients, 7(4), 2801–2822. https://doi.org/10.3390/nu7042801
10. *see mushroom category for individual mushrooms* Wachtel-Galor S, Yuen J, Buswell JA, et al. Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92757/
11. Rao, V., Balachandran, B., Shen, H., Logan, A., & Rao, L. (2011). In vitro and in vivo antioxidant properties of the plant-based supplement greens+™. International journal of molecular sciences, 12(8), 4896–4908. https://doi.org/10.3390/ijms12084896
Topics
Select a topic to learn more about the published research into nutrition and physiology that guides to our content.
Digestion
1.https://www.apa.org/topics/stress/body
2.https://www.sciencedaily.com/releases/2016/06/160609115127.htm
3.https://pubmed.ncbi.nlm.nih.gov/24668555/
4.https://pubmed.ncbi.nlm.nih.gov/24668555/
5.https://www.clinicaleducation.org/resources/reviews/the-role-of-hcl-in-gastric-function-and-health/
6. Shaik, F. A., Singh, N., Arakawa, M., Duan, K., Bhullar, R. P., & Chelikani, P. (2016). Bitter taste receptors: Extraoral roles in pathophysiology. The international journal of biochemistry & cell biology, 77(Pt B), 197–204. https://doi.org/10.1016/j.biocel.2016.03.011
1.https://www.clinicaleducation.org/resources/reviews/the-use-of-vitamin-u-for-gastric-ulcer-recovery/
2. Patel, A.D. et al. (2012). Review on Biochemical Importance of Vitamin-U. J. Chem. Pharm. Res., 4(1), 209-215. Retrieved from: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.694.9840&rep=rep1&type=pdf
3. Rao, R., & Samak, G. (2012). Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions. Journal of epithelial biology & pharmacology, 5(Suppl 1-M7), 47–54. https://doi.org/10.2174/1875044301205010047
4. Carlson, J. L., Erickson, J. M., Lloyd, B. B., & Slavin, J. L. (2018). Health Effects and Sources of Prebiotic Dietary Fiber. Current developments in nutrition, 2(3), nzy005. https://doi.org/10.1093/cdn/nzy005
1. Lim, H. S., Kim, S. K., & Hong, S. J. (2018). Food Elimination Diet and Nutritional Deficiency in Patients with Inflammatory Bowel Disease. Clinical nutrition research, 7(1), 48–55. https://doi.org/10.7762/cnr.2018.7.1.48
2. Mu, Q., Kirby, J., Reilly, C. M., & Luo, X. M. (2017). Leaky Gut As a Danger Signal for Autoimmune Diseases. Frontiers in immunology, 8, 598. https://doi.org/10.3389/fimmu.2017.00598
4. Holscher H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut microbes, 8(2), 172–184. https://doi.org/10.1080/19490976.2017.1290756
5.https://www.clinicaleducation.org/resources/reviews/the-use-of-vitamin-u-for-gastric-ulcer-recovery/
6. Rao, R., & Samak, G. (2012). Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions. Journal of epithelial biology & pharmacology, 5(Suppl 1-M7), 47–54. https://doi.org/10.2174/1875044301205010047
7. Peyrot des Gachons, C., & Breslin, P. A. (2016). Salivary Amylase: Digestion and Metabolic Syndrome. Current diabetes reports, 16(10), 102. https://doi.org/10.1007/s11892-016-0794-7
8. McMullen, M. K., Whitehouse, J. M., & Towell, A. (2015). Bitters: Time for a New Paradigm. Evidence-based complementary and alternative medicine : eCAM, 2015, 670504. https://doi.org/10.1155/2015/670504
9. Brugger, D., & Windisch, W. M. (2016). Subclinical zinc deficiency impairs pancreatic digestive enzyme activity and digestive capacity of weaned piglets. The British journal of nutrition, 116(3), 425–433. https://doi.org/10.1017/S0007114516002105
10. Klinder, A., Shen, Q., Heppel, S., Lovegrove, J. A., Rowland, I., & Tuohy, K. M. (2016). Impact of increasing fruit and vegetables and flavonoid intake on the human gut microbiota. Food & function, 7(4), 1788–1796. https://doi.org/10.1039/c5fo01096a
11. Skrovanek, S., DiGuilio, K., Bailey, R., Huntington, W., Urbas, R., Mayilvaganan, B., Mercogliano, G., & Mullin, J. M. (2014). Zinc and gastrointestinal disease. World journal of gastrointestinal pathophysiology, 5(4), 496–513. https://doi.org/10.4291/wjgp.v5.i4.496
1.https://www.clinicaleducation.org/resources/reviews/the-role-of-hcl-in-gastric-function-and-health/
2. Brugger D, Windisch W. Subclinical Zinc Deficiency Impairs Pancreatic Digestive Enzyme Activity and Digestive Capacity of Weaned Piglets. British Journal of Nutrition. 2016.
1. Bischoff, S. C., Barbara, G., Buurman, W., Ockhuizen, T., Schulzke, J. D., Serino, M., Tilg, H., Watson, A., & Wells, J. M. (2014). Intestinal permeability--a new target for disease prevention and therapy. BMC gastroenterology, 14, 189. https://doi.org/10.1186/s12876-014-0189-7
2. Skrovanek, S., DiGuilio, K., Bailey, R., Huntington, W., Urbas, R., Mayilvaganan, B., Mercogliano, G., & Mullin, J. M. (2014). Zinc and gastrointestinal disease. World journal of gastrointestinal pathophysiology, 5(4), 496–513. https://doi.org/10.4291/wjgp.v5.i4.496
3. Konturek, P. C., Brzozowski, T., & Konturek, S. J. (2011). Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 62(6), 591–599.
4. Holscher H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut microbes, 8(2), 172–184. https://doi.org/10.1080/19490976.2017.1290756
5. CHENEY, G., WAXLER, S. H., & MILLER, I. J. (1956). Vitamin U therapy of peptic ulcer; experience at San Quentin Prison. California medicine, 84(1), 39–42.
6. Rao, R., & Samak, G. (2012). Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions. J Epithel Biol Pharmacology. doi:doi:10.2174/1875044301205010047.
1. Magnúsdóttir, S., Ravcheev, D., de Crécy-Lagard, V., & Thiele, I. (2015). Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes. Frontiers in genetics, 6, 148. https://doi.org/10.3389/fgene.2015.00148
2. Cenit, M. C., Sanz, Y., & Codoñer-Franch, P. (2017). Influence of gut microbiota on neuropsychiatric disorders. World journal of gastroenterology, 23(30), 5486–5498. https://doi.org/10.3748/wjg.v23.i30.5486
3. Sokol H, Leducq V, Aschard H, et al Fungal microbiota dysbiosis in IBD Gut 2017;66:1039-1048.
4. Yao, K., Zeng, L., He, Q., Wang, W., Lei, J., & Zou, X. (2017). Effect of Probiotics on Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus: A Meta-Analysis of 12 Randomized Controlled Trials. Medical science monitor : international medical journal of experimental and clinical research, 23, 3044–3053. https://doi.org/10.12659/msm.902600.
1.https://chriskresser.com/role-of-gut-microbiome-in-the-immune-system/
2. Kau, A. L., Ahern, P. P., Griffin, N. W., Goodman, A. L., & Gordon, J. I. (2011). Human nutrition, the gut microbiome and the immune system. Nature, 474(7351), 327–336. https://doi.org/10.1038/nature10213
3. Statovci, D., Aguilera, M., MacSharry, J., & Melgar, S. (2017). The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces. Frontiers in immunology, 8, 838. https://doi.org/10.3389/fimmu.2017.00838
1. Gao, X., Cao, Q., Cheng, Y., Zhao, D., Wang, Z., Yang, H., ... & Li, X. (2018). Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response. Proceedings of the National Academy of Sciences, 115(13), E2960-E2969.
1.https://www.niddk.nih.gov/health-information/digestive-diseases/constipation/symptoms-causes
2. Weickert, M. O., & Pfeiffer, A. F. (2008). Metabolic effects of dietary fiber consumption and prevention of diabetes. The Journal of nutrition, 138(3), 439–442. https://doi.org/10.1093/jn/138.3.439
3. Anderson, J. W., Baird, P., Davis, R. H., Jr, Ferreri, S., Knudtson, M., Koraym, A., Waters, V., & Williams, C. L. (2009). Health benefits of dietary fiber. Nutrition reviews, 67(4), 188–205. https://doi.org/10.1111/j.1753-4887.2009.00189.x
4. Mori, S., Tomita, T., Fujimura, K., Asano, H., Ogawa, T., Yamasaki, T., Kondo, T., Kono, T., Tozawa, K., Oshima, T., Fukui, H., Kimura, T., Watari, J., & Miwa, H. (2019). A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation. Journal of neurogastroenterology and motility, 25(4), 563–575. https://doi.org/10.5056/jnm18194
6.Kids and Exercise (for Parents) - Nemours KidsHealth or https://kidshealth.org/en/parents/exercise.html
1. Riegler, G., & Esposito, I. (2001). Bristol scale stool form. A still valid help in medical practice and clinical research. Techniques in coloproctology, 5(3), 163–164. https://doi.org/10.1007/s101510100019
2. Zuckerman, G. R., Trellis, D. R., Sherman, T. M., & Clouse, R. E. (1995). An objective measure of stool color for differentiating upper from lower gastrointestinal bleeding. Digestive diseases and sciences, 40(8), 1614–1621. https://doi.org/10.1007/BF02212679
3.https://www.mayoclinic.org/diseases-conditions/constipation/symptoms-causes/syc-20354253
Energy + Mood + Stress
1. Breit, S., Kupferberg, A., Rogler, G., & Hasler, G. (2018). Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders. Frontiers in psychiatry, 9, 44. https://doi.org/10.3389/fpsyt.2018.00044
2. Pal, G. K., Velkumary, S., & Madanmohan (2004). Effect of short-term practice of breathing exercises on autonomic functions in normal human volunteers. The Indian journal of medical research, 120(2), 115–121.
3. Godek D, Freeman AM. Physiology, Diving Reflex. [Updated 2020 Sep 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538245/
1. Pal, G. K., Ganesh, V., Karthik, S., Nanda, N., & Pal, P. (2014). The effects of short-term relaxation therapy on indices of heart rate variability and blood pressure in young adults. American journal of health promotion : AJHP, 29(1), 23–28. https://doi.org/10.4278/ajhp.130131-QUAN-52
2. Streeter, C. C., Gerbarg, P. L., Whitfield, T. H., Owen, L., Johnston, J., Silveri, M. M., Gensler, M., Faulkner, C. L., Mann, C., Wixted, M., Hernon, A. M., Nyer, M. B., Brown, E. R., & Jensen, J. E. (2017). Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study. Journal of Alternative and Complementary Medicine (New York, N.Y.), 23(3), 201–207. https://doi.org/10.1089/acm.2016.0140
1.https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
2. Kennedy D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients, 8(2), 68. https://doi.org/10.3390/nu8020068
1. Smith, S. M., & Vale, W. W. (2006). The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues in clinical neuroscience, 8(4), 383–395. https://doi.org/10.31887/DCNS.2006.8.4/ssmith
2. Veldhuis JD, Sharma A, Roelfsema F. Age-dependent and gender-dependent regulation of hypothalamic-adrenocorticotropic-adrenal axis. Endocrinol Metab Clin North Am. 2013 Jun;42(2):201-25. doi: 10.1016/j.ecl.2013.02.002. Epub 2013 Mar 13. PMID: 23702398; PMCID: PMC3675779.
3. Al-Dujaili, E., Ashmore, S., & Tsang, C. (2019). A Short Study Exploring the Effect of the Glycaemic Index of the Diet on Energy intake and Salivary Steroid Hormones. Nutrients, 11(2), 260. https://doi.org/10.3390/nu11020260
4. Hooper, M.H., Carr, A. & Marik, P.E. The adrenal-vitamin C axis: from fish to guinea pigs and primates. Crit Care 23, 29 (2019). https://doi.org/10.1186/s13054-019-2332-x
1. Morisco, F., Lembo, V., Mazzone, G., Camera, S., & Caporaso, N. (2014). Coffee and liver health. Journal of clinical gastroenterology, 48 Suppl 1, S87–S90. https://doi.org/10.1097/MCG.0000000000000240
2. Clifford, T., Howatson, G., West, D. J., & Stevenson, E. J. (2015). The potential benefits of red beetroot supplementation in health and disease. Nutrients, 7(4), 2801–2822. https://doi.org/10.3390/nu7042801
3. Gupta, V., Mah, X. J., Garcia, M. C., Antonypillai, C., & van der Poorten, D. (2015). Oily fish, coffee and walnuts: Dietary treatment for nonalcoholic fatty liver disease. World journal of gastroenterology, 21(37), 10621–10635. https://doi.org/10.3748/wjg.v21.i37.10621
1. Lindsay EK, Young S, Brown KW, Smyth JM, Creswell JD. Mindfulness training reduces loneliness and increases social contact in a randomized controlled trial. Proc Natl Acad Sci U S A. 2019;116(9):3488-3493. doi:10.1073/pnas.1813588116
3. Goyal M, Singh S, Sibinga EM, Gould NF, Rowland-Seymour A, Sharma R, Berger Z, Sleicher D, Maron DD, Shihab HM, Ranasinghe PD, Linn S, Saha S, Bass EB, Haythornthwaite JA. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern Med. 2014 Mar;174(3):357-68. doi: 10.1001/jamainternmed.2013.13018. PMID: 24395196; PMCID: PMC4142584.
4. Rusch HL, Rosario M, Levison LM, et al. The effect of mindfulness meditation on sleep quality: a systematic review and meta-analysis of randomized controlled trials. Ann N Y Acad Sci. 2019;1445(1):5-16. doi:10.1111/nyas.13996
1. Statovci, D., Aguilera, M., MacSharry, J., & Melgar, S. (2017). The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces. Frontiers in immunology, 8, 838. https://doi.org/10.3389/fimmu.2017.00838
1. Nutritional Therapy Association. (2017). Hydration Module Slides [PDF document]. Retrieved from https://nta.brightspace.com/d2l/le/content/10074/viewContent/101881/View
2. Ballantyne, Sarah (2017). Paleo Principles. Las Vegas, NV: Victory Belt Publishing, Inc.
3. Tardy, A. L., Pouteau, E., Marquez, D., Yilmaz, C., & Scholey, A. (2020). Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Nutrients, 12(1), 228. https://doi.org/10.3390/nu12010228
4. Haas, Elson. (2006). Staying Healthy with Nutrition. Berkeley, CA: Celestial Arts.
5. Lynch SR, Cook JD. Interaction of vitamin C and iron. Ann N Y Acad Sci. 1980;355:32-44. doi: 10.1111/j.1749-6632.1980.tb21325.x. PMID: 6940487.
6. Ballantyne, Sarah. (2018, February 19).Is Breakfast The Most Important Meal of the Day? New Science Has Answers! The Paleo Mom
7.https://www.thepaleomom.com/breakfast-important-meal-day-new-science-answers/
8.https://www.hsph.harvard.edu/nutritionsource/food-features/oats/
9.https://www.hsph.harvard.edu/nutritionsource/food-features/chia-seeds/
1.https://www.psychiatry.org/newsroom/apa-public-opinion-poll-annual-meeting-2018
2.Thakur, K., Tomar, S. K., Singh, A. K., Mandal, S., & Arora, S. (2017). Riboflavin and health: A review of recent human research. Critical reviews in food science and nutrition, 57(17), 3650–3660. https://doi.org/10.1080/10408398.2016.1145104
3.Almeida, O. P., Ford, A. H., Hirani, V., Singh, V., vanBockxmeer, F. M., McCaul, K., & Flicker, L. (2014). B vitamins to enhance treatment response to antidepressants in middle-aged and older adults: results from the B-VITAGE randomised, double-blind, placebo-controlled trial. The British journal of psychiatry : the journal of mental science, 205(6), 450–457. https://doi.org/10.1192/bjp.bp.114.145177
4.Kirkland, A. E., Sarlo, G. L., & Holton, K. F. (2018). The Role of Magnesium in Neurological Disorders. Nutrients, 10(6), 730. https://doi.org/10.3390/nu10060730
5. Sartori SB, et al. (2012). Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment. DOI: 10.1016/j.neuropharm.2011.07.027
6. Reddy, P., & Edwards, L. R. (2019). Magnesium Supplementation in Vitamin D Deficiency. American journal of therapeutics, 26(1), e124–e132. https://doi.org/10.1097/MJT.0000000000000538
7. Boyle NB, et. al. (2017). The effects of magnesium supplementation on subjective anxiety and stress – A systematic review. DOI: 10.3390/nu9050429
8.http://www.biomed.cas.cz/physiolres/pdf/64%20Suppl%202/64_S101.pdf
9. Sue Penckofer, Mary Byrn, William Adams, Mary Ann Emanuele, Patricia Mumby, Joanne Kouba, Diane E. Wallis, "Vitamin D Supplementation Improves Mood in Women with Type 2 Diabetes", Journal of Diabetes Research, vol. 2017, Article ID 8232863, 11 pages, 2017. https://doi.org/10.1155/2017/8232863
1.https://www.health.harvard.edu/blog/nutritional-strategies-to-ease-anxiety-201604139441
2.https://www.nimh.nih.gov/health/topics/anxiety-disorders/index.shtml
3. Jaatinen, N., Korpela, R., Poussa, T., Turpeinen, A., Mustonen, S., Merilahti, J., & Peuhkuri, K. (2014). Effects of daily intake of yoghurt enriched with bioactive components on chronic stress responses: a double-blinded randomized controlled trial. International journal of food sciences and nutrition, 65(4), 507–514. https://doi.org/10.3109/09637486.2014.880669
4. Hansen, A. L., Olson, G., Dahl, L., Thornton, D., Grung, B., Graff, I. E., Frøyland, L., & Thayer, J. F. (2014). Reduced anxiety in forensic inpatients after a long-term intervention with Atlantic salmon. Nutrients, 6(12), 5405–5418. https://doi.org/10.3390/nu6125405
5. White, D. J., de Klerk, S., Woods, W., Gondalia, S., Noonan, C., & Scholey, A. B. (2016). Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial. Nutrients, 8(1), 53. https://doi.org/10.3390/nu8010053
6. Mao, J. J., Xie, S. X., Keefe, J. R., Soeller, I., Li, Q. S., & Amsterdam, J. D. (2016). Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial. Phytomedicine : international journal of phytotherapy and phytopharmacology, 23(14), 1735–1742. https://doi.org/10.1016/j.phymed.2016.10.012
1.Glycogen Metabolism - Biochemistry - NCBI Bookshelf (nih.gov)
2. Gross, L. S., Li, L., Ford, E. S., & Liu, S. (2004). Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. The American journal of clinical nutrition, 79(5), 774–779. https://doi.org/10.1093/ajcn/79.5.774
3. Oomen, C. M., Ocké, M. C., Feskens, E. J., van Erp-Baart, M. A., Kok, F. J., & Kromhout, D. (2001). Association between trans fatty acid intake and 10-year risk of coronary heart disease in the Zutphen Elderly Study: a prospective population-based study. Lancet (London, England), 357(9258), 746–751. https://doi.org/10.1016/s0140-6736(00)04166-0
1.https://www.hsph.harvard.edu/nutritionsource/vitamins/vitamin-b/
2.https://www.healthline.com/health/b12-vitamins-for-energy
3. Zhao, J. V., Schooling, C. M., & Zhao, J. X. (2018). The effects of folate supplementation on glucose metabolism and risk of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Annals of epidemiology, 28(4), 249–257.e1. https://doi.org/10.1016/j.annepidem.2018.02.001
4.https://www.health.harvard.edu/mind-and-mood/probiotics-may-help-boost-mood-and-cognitive-function
6. Clifford, T., Howatson, G., West, D. J., & Stevenson, E. J. (2015). The potential benefits of red beetroot supplementation in health and disease. Nutrients, 7(4), 2801–2822. https://doi.org/10.3390/nu7042801
7.https://www.medicalnewstoday.com/articles/153188#imbalance
8.https://www.news-medical.net/health/Health-Benefits-of-Prebiotics.aspx
9. Davani-Davari, D., Negahdaripour, M., Karimzadeh, I., Seifan, M., Mohkam, M., Masoumi, S. J., Berenjian, A., & Ghasemi, Y. (2019). Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods (Basel, Switzerland), 8(3), 92. https://doi.org/10.3390/foods8030092
Men's, Women's, and Children's Health and Nutrition
1. Bohon, T. M., & Goolsby, M. A. (2013). The Role of Vitamin D Supplements in Women's Health. Clinical medicine insights. Women's health, 6, 67–70. https://doi.org/10.4137/CMWH.S11067
2.https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
3. Blom, H. J., & Smulders, Y. (2011). Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects. Journal of inherited metabolic disease, 34(1), 75–81. https://doi.org/10.1007/s10545-010-9177-4
4. Ravaglia, G., Forti, P., Maioli, F., Servadei, L., Martelli, M., Brunetti, N., Bastagli, L., Cucinotta, D., & Mariani, E. (2005). Folate, but not homocysteine, predicts the risk of fracture in elderly persons. The journals of gerontology. Series A, Biological sciences and medical sciences, 60(11), 1458–1462. https://doi.org/10.1093/gerona/60.11.1458
5. Fekete, K., Berti, C., Trovato, M., Lohner, S., Dullemeijer, C., Souverein, O. W., Cetin, I., & Decsi, T. (2012). Effect of folate intake on health outcomes in pregnancy: a systematic review and meta-analysis on birth weight, placental weight and length of gestation. Nutrition journal, 11, 75. https://doi.org/10.1186/1475-2891-11-75
6.https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/#h4
7.https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/#h2
8. Lyckholm, L., Heddinger, S. P., Parker, G., Coyne, P. J., Ramakrishnan, V., Smith, T. J., & Henkin, R. I. (2012). A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders. Journal of pain & palliative care pharmacotherapy, 26(2), 111–114. https://doi.org/10.3109/15360288.2012.676618
9. Liu, E., Pimpin, L., Shulkin, M., Kranz, S., Duggan, C. P., Mozaffarian, D., & Fawzi, W. W. (2018). Effect of Zinc Supplementation on Growth Outcomes in Children under 5 Years of Age. Nutrients, 10(3), 377. https://doi.org/10.3390/nu10030377
10. Haase, H., & Rink, L. (2009). The immune system and the impact of zinc during aging. Immunity & ageing : I & A, 6, 9. https://doi.org/10.1186/1742-4933-6-9
11.https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/#h2
12.https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
13. Walker, A. F., De Souza, M. C., Vickers, M. F., Abeyasekera, S., Collins, M. L., & Trinca, L. A. (1998). Magnesium supplementation alleviates premenstrual symptoms of fluid retention. Journal of women's health, 7(9), 1157–1165. https://doi.org/10.1089/jwh.1998.7.1157
14. Barbagallo, M., & Dominguez, L. J. (2015). Magnesium and type 2 diabetes. World journal of diabetes, 6(10), 1152–1157. https://doi.org/10.4239/wjd.v6.i10.1152
15. Kiecolt-Glaser, J. K., Belury, M. A., Andridge, R., Malarkey, W. B., & Glaser, R. (2011). Omega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial. Brain, behavior, and immunity, 25(8), 1725–1734. https://pubmed.ncbi.nlm.nih.gov/21784145/
16. Sergeant, S., Rahbar, E., & Chilton, F. H. (2016). Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. European journal of pharmacology, 785, 77–86. https://doi.org/10.1016/j.ejphar.2016.04.020
17.https://diabetes.diabetesjournals.org/content/64/6/2116.long
18.https://speakingofwomenshealth.com/health-library/improving-your-health-with-fiber
19. Blood sugar spikes: Causes, symptoms, and prevention (medicalnewstoday.com)
1.https://ndnr.com/womens-health/the-relationship-between-adrenal-function-and-menopausal-symptoms-2/
2.https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/
3. Chopra S, Sharma KA, Ranjan P, Malhotra A, Vikram NK, Kumari A. Weight Management Module for Perimenopausal Women: A Practical Guide for Gynecologists. J Midlife Health. 2019;10(4):165-172. doi:10.4103/jmh.JMH_155_19
4. Chen LR, Ko NY, Chen KH. Isoflavone Supplements for Menopausal Women: A Systematic Review. Nutrients. 2019;11(11):2649. Published 2019 Nov 4. doi:10.3390/nu11112649
5.https://www.health.harvard.edu/womens-health/perimenopause-rocky-road-to-menopause
7.https://my.clevelandclinic.org/health/diseases/21608-perimenopause
8.https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
9. Lips, P., & van Schoor, N. M. (2011). The effect of vitamin D on bone and osteoporosis. Best practice & research. Clinical endocrinology & metabolism, 25(4), 585–591. https://doi.org/10.1016/j.beem.2011.05.002
10.https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2796.2008.02008.x
11.https://ods.od.nih.gov/factsheets/BlackCohosh-HealthProfessional/
12. Ruhlen RL,Sun G,Sauter,E. Black Cohosh: Insights into its Mechanism(s) of Action. Integr Med Insights. 2008; 3: 21–32. Published online August 27, 2008.
13. https://www.mdpi.com/2073-4409/8/12/1642/htm
14. What Does Estrogen Do?, The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 31A–32A, https://doi.org/10.1210/jc.2014-v99i4-31A
15. Djokic, G., Vojvodić, P., Korcok, D., Agic, A., Rankovic, A., Djordjevic, V., Vojvodic, A., Vlaskovic-Jovicevic, T., Peric-Hajzler, Z., Matovic, D., Vojvodic, J., Sijan, G., Wollina, U., Tirant, M., Thuong, N. V., Fioranelli, M., & Lotti, T. (2019). The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open access Macedonian journal of medical sciences, 7(18), 3101–3105. https://doi.org/10.3889/oamjms.2019.771
16.https://www.sciencedirect.com/science/article/pii/S0028390811003054?via%3Dihub
17. Park, H., Parker, G. L., Boardman, C. H., Morris, M. M., & Smith, T. J. (2011). A pilot phase II trial of magnesium supplements to reduce menopausal hot flashes in breast cancer patients. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 19(6), 859–863. https://doi.org/10.1007/s00520-011-1099-7
18.https://www.sciencedirect.com/science/article/pii/S0028390811003054?via%3Dihub
19. Yutaka Nakaya, Asako Minami, Nagakatsu Harada, Sadaichi Sakamoto, Yasuharu Niwa, Masaharu Ohnaka, Taurine improves insulin sensitivity in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous type 2 diabetes, The American Journal of Clinical Nutrition, Volume 71, Issue 1, January 2000, Pages 54–58, https://doi.org/10.1093/ajcn/71.1.54
20. Baker, J. M., Al-Nakkash, L., & Herbst-Kralovetz, M. M. (2017). Estrogen-gut microbiome axis: Physiological and clinical implications. Maturitas, 103, 45–53. https://doi.org/10.1016/j.maturitas.2017.06.025
21. Caine, J. J., & Geracioti, T. D. (2016). Taurine, energy drinks, and neuroendocrine effects. Cleveland Clinic journal of medicine, 83(12), 895–904. https://doi.org/10.3949/ccjm.83a.15050
22.https://www.ahajournals.org/doi/10.1161/CIR.0000000000000709
23. Hu, Y., Hu, F. B., & Manson, J. E. (2019). Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants. Journal of the American Heart Association, 8(19), e013543. https://doi.org/10.1161/JAHA.119.013543
24. Mocking, R. J., Harmsen, I., Assies, J., Koeter, M. W., Ruhé, H. G., & Schene, A. H. (2016). Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder. Translational psychiatry, 6(3), e756. https://doi.org/10.1038/tp.2016.29
1.https://www.medicalnewstoday.com/articles/320310
2.https://www.medicalnewstoday.com/articles/325292#riboflavin
3.https://www.who.int/elena/bbc/zinc_stunting/en/
4.https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/
5. Mesías, M., Seiquer, I., & Navarro, M. P. (2013). Iron nutrition in adolescence. Critical reviews in food science and nutrition, 53(11), 1226–1237. https://doi.org/10.1080/10408398.2011.564333
6.https://ods.od.nih.gov/factsheets/Molybdenum-HealthProfessional/
8. Bai, X. Y., Qu, X., Jiang, X., Xu, Z., Yang, Y., Su, Q., Wang, M., & Wu, H. (2015). Association between Dietary Vitamin C Intake and Risk of Prostate Cancer: A Meta-analysis Involving 103,658 Subjects. Journal of Cancer, 6(9), 913–921. https://doi.org/10.7150/jca.12162
9.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010824/
10. Durairajanayagam, D., Agarwal, A., Ong, C., & Prashast, P. (2014). Lycopene and male infertility. Asian journal of andrology, 16(3), 420–425. https://doi.org/10.4103/1008-682X.126384
11. Chen, P., Zhang, W., Wang, X., Zhao, K., Negi, D. S., Zhuo, L., Qi, M., Wang, X., & Zhang, X. (2015). Lycopene and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis. Medicine, 94(33), e1260. https://doi.org/10.1097/MD.0000000000001260
12. Santos, J. R., Gois, A. M., Mendonça, D. M., & Freire, M. A. (2014). Nutritional status, oxidative stress and dementia: the role of selenium in Alzheimer's disease. Frontiers in aging neuroscience, 6, 206. https://doi.org/10.3389/fnagi.2014.00206
1. Sauer, A., Vela, H., Vela, G., Stark, P., Barrera-Juarez, E., Grabrucker, A. Zinc Deficiency in Men Over 50 and Its Implications in Prostate Disorders, Frontiers in Oncology, Aug. 2020
2. Fallah, A., Azadeh, M., Abasalt Hosseinzadeh, C., Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men’s Health, Germination, Sperm Quality, and Fertilization, Journal of Reproduction & Infertility, Apr. 2018
3.https://www.medicalnewstoday.com/articles/324856
4.https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
5.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901845/
6.https://www.hsph.harvard.edu/nutritionsource/vitamin-d/
7.https://www.healthline.com/nutrition/17-health-benefits-of-omega-3
1. Bos, D. J., Oranje, B., Veerhoek, E. S., Van Diepen, R. M., Weusten, J. M., Demmelmair, H., Koletzko, B., de Sain-van der Velden, M. G., Eilander, A., Hoeksma, M., & Durston, S. (2015). Reduced Symptoms of Inattention after Dietary Omega-3 Fatty Acid Supplementation in Boys with and without Attention Deficit/Hyperactivity Disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(10), 2298–2306. https://doi.org/10.1038/npp.2015.73
2. Brigham, E. P., Woo, H., McCormack, M., Rice, J., Koehler, K., Vulcain, T., Wu, T., Koch, A., Sharma, S., Kolahdooz, F., Bose, S., Hanson, C., Romero, K., Diette, G., & Hansel, N. N. (2019). Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children. American journal of respiratory and critical care medicine, 199(12), 1478–1486. https://doi.org/10.1164/rccm.201808-1474OC
3. Allison S. (2004). Fluid, electrolytes and nutrition. Clinical medicine (London, England), 4(6), 573–578. https://doi.org/10.7861/clinmedicine.4-6-573
4. Jorde, R., Sneve, M., Figenschau, Y., Svartberg, J. and Waterloo, K. (2008), Effects of vitamin D supplementation on symptoms of depression in overweight and obese subjects: randomized double blind trial. Journal of Internal Medicine, 264: 599-609. https://doi.org/10.1111/j.1365-2796.2008.02008.x
5. Urashima, M., Segawa, T., Okazaki, M., Kurihara, M., Wada, Y., & Ida, H. (2010). Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. The American journal of clinical nutrition, 91(5), 1255–1260. https://doi.org/10.3945/ajcn.2009.29094
1. Breneman, C. B., & Tucker, L. (2013). Dietary fibre consumption and insulin resistance - the role of body fat and physical activity. The British journal of nutrition, 110(2), 375–383. https://doi.org/10.1017/S0007114512004953
2. Jarvill-Taylor, K. J., Anderson, R. A., & Graves, D. J. (2001). A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. Journal of the American College of Nutrition, 20(4), 327–336. https://doi.org/10.1080/07315724.2001.10719053
3. Jarvill-Taylor, K. J., Anderson, R. A., & Graves, D. J. (2001). A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. Journal of the American College of Nutrition, 20(4), 327–336. https://doi.org/10.1080/07315724.2001.10719053
4. Na, L. X., Zhang, Y. L., Li, Y., Liu, L. Y., Li, R., Kong, T., & Sun, C. H. (2011). Curcumin improves insulin resistance in skeletal muscle of rats. Nutrition, metabolism, and cardiovascular diseases : NMCD, 21(7), 526–533. https://doi.org/10.1016/j.numecd.2009.11.009
5. Liljeberg, H., & Björck, I. (1998). Delayed gastric emptying rate may explain improved glycaemia in healthy subjects to a starchy meal with added vinegar. European journal of clinical nutrition, 52(5), 368–371. https://doi.org/10.1038/sj.ejcn.1600572
6. Radulian, G., Rusu, E., Dragomir, A. et al. Metabolic effects of low glycaemic index diets. Nutr J 8, 5 (2009). https://doi.org/10.1186/1475-2891-8-5
7. Guerrero-Romero, F., Tamez-Perez, H. E., González-González, G., Salinas-Martínez, A. M., Montes-Villarreal, J., Treviño-Ortiz, J. H., & Rodríguez-Morán, M. (2004). Oral magnesium supplementation improves insulin sensitivity in non-diabetic subjects with insulin resistance. A double-blind placebo-controlled randomized trial. Diabetes & metabolism, 30(3), 253–258. https://doi.org/10.1016/s1262-3636(07)70116-7
1. Lopresti A. L. (2020). The Effects of Psychological and Environmental Stress on Micronutrient Concentrations in the Body: A Review of the Evidence. Advances in nutrition (Bethesda, Md.), 11(1), 103–112. https://doi.org/10.1093/advances/nmz082
2.https://www.actascientific.com/ASNH/pdf/ASNH-03-0285.pdf
3.https://nutritionreview.org/2018/11/gastric-balance-heartburn-caused-excess-acid/
1. Newmaster, S. G., Grguric, M., Shanmughanandhan, D., Ramalingam, S., & Ragupathy, S. (2013). DNA barcoding detects contamination and substitution in North American herbal products. BMC medicine, 11, 222. https://doi.org/10.1186/1741-7015-11-222
1.Magnesium - Health Professional Fact Sheet (nih.gov)
2. J S Lindberg, M M Zobitz, J R Poindexter & C Y Pak (1990) Magnesium bioavailability from magnesium citrate and magnesium oxide., Journal of the American College of Nutrition, 9:1, 48-55, DOI: 10.1080/07315724.1990.10720349
4. Schuchardt, J. P., & Hahn, A. (2017). Intestinal Absorption and Factors Influencing Bioavailability of Magnesium-An Update. Current nutrition and food science, 13(4), 260–278. https://doi.org/10.2174/1573401313666170427162740
5. Ferreira, I., Ortigoza, Á., & Moore, P. (2019). Magnesium and malic acid supplement for fibromyalgia. Suplemento de magnesio y ácido málico para fibromialgia. Medwave, 19(4), e7633. https://doi.org/10.5867/medwave.2019.04.7632
6. Zarate, C., Duman, R. S., Liu, G., Sartori, S., Quiroz, J., & Murck, H. (2013). New paradigms for treatment-resistant depression. Annals of the New York Academy of Sciences, 1292, 21–31. https://doi.org/10.1111/nyas.12223
7. Classen H. G. (2004). Magnesium orotate--experimental and clinical evidence. Romanian journal of internal medicine = Revue roumaine de medecine interne, 42(3), 491–501.
1. Pizzorno, Joseph. “Glutathione!.” Integrative medicine (Encinitas, Calif.) vol. 13,1 (2014): 8-12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684116/
2. Hyman, Mark. “Essential Glutathione: The Mother of All Antioxidants”
1. Shi, L. H., Balakrishnan, K., Thiagarajah, K., Mohd Ismail, N. I., & Yin, O. S. (2016). Beneficial Properties of Probiotics. Tropical life sciences research, 27(2), 73–90. https://doi.org/10.21315/tlsr2016.27.2.6
2. Cheng, D., Song, J., Xie, M., & Song, D. (2019). The bidirectional relationship between host physiology and microbiota and health benefits of probiotics: A review. Trends in Food Science & Technology, 91, 426-435.
3. Mcfarlin, B. K., Henning, A. L., Bowman, E. M., Gary, M. A., & Carbajal, K. M. (2017). Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers. World Journal of Gastrointestinal Pathophysiology, 8(3), 117. doi:10.4291/wjgp.v8.i3.117
Immune and Inflammation
1. Carr, A., & Maggini, S. (2017). Vitamin C and Immune Function. Nutrients, 9(11), 1211. MDPI AG. Retrieved from http://dx.doi.org/10.3390/nu9111211
2. Hallberg, L., & Hulthén, L. (2000). Prediction of dietary iron absorption: an algorithm for calculating absorption and bioavailability of dietary iron. The American journal of clinical nutrition, 71(5), 1147–1160. https://doi.org/10.1093/ajcn/71.5.1147
1. Kau, A. L., Ahern, P. P., Griffin, N. W., Goodman, A. L., & Gordon, J. I. (2011). Human nutrition, the gut microbiome and the immune system. Nature, 474(7351), 327–336. https://doi.org/10.1038/nature10213
2.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337124/
3. Gombart, A. F., Pierre, A., & Maggini, S. (2020). A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients, 12(1), 236. https://doi.org/10.3390/nu12010236
1. Ben-Arye, E., Dudai, N., Eini, A., Torem, M., Schiff, E., & Rakover, Y. (2011). Treatment of upper respiratory tract infections in primary care: a randomized study using aromatic herbs. Evidence-based complementary and alternative medicine : eCAM, 2011, 690346. https://doi.org/10.1155/2011/690346
2. Widrig, R., Suter, A., Saller, R., & Melzer, J. (2007). Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study. Rheumatology international, 27(6), 585–591. https://doi.org/10.1007/s00296-007-0304-y
3. Tiralongo, E., Wee, S. S., & Lea, R. A. (2016). Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients, 8(4), 182. https://doi.org/10.3390/nu8040182
1. Hannoodee S, Nasuruddin DN. Acute Inflammatory Response. [Updated 2020 Nov 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556083/
2. Furman, D., Campisi, J., Verdin, E. et al. Chronic inflammation in the etiology of disease across the life span. Nat Med 25, 1822–1832 (2019). https://doi.org/10.1038/s41591-019-0675-0
3. Pahwa R, Goyal A, Bansal P, et al. Chronic Inflammation. [Updated 2021 Aug 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK493173/
5. Jafarirad, S., Ayoobi, N., Karandish, M., Jalali, M. T., Haghighizadeh, M. H., & Jahanshahi, A. (2018). Dark Chocolate Effect on Serum Adiponectin, Biochemical and Inflammatory Parameters in Diabetic Patients: A Randomized Clinical Trial. International journal of preventive medicine, 9, 86. https://doi.org/10.4103/ijpvm.IJPVM_339_17
6. Lila M. A. (2004). Anthocyanins and Human Health: An In Vitro Investigative Approach. Journal of biomedicine & biotechnology, 2004(5), 306–313. https://doi.org/10.1155/S111072430440401X
7. Yoneyama, S., Miura, K., Sasaki, S., Yoshita, K., Morikawa, Y., Ishizaki, M., Kido, T., Naruse, Y., & Nakagawa, H. (2007). Dietary intake of fatty acids and serum C-reactive protein in Japanese. Journal of epidemiology, 17(3), 86–92. https://doi.org/10.2188/jea.17.86
8. Arunima, S., & Rajamohan, T. (2013). Effect of virgin coconut oil enriched diet on the antioxidant status and paraoxonase 1 activity in ameliorating the oxidative stress in rats - a comparative study. Food & function, 4(9), 1402–1409. https://doi.org/10.1039/c3fo60085h
1. Nagpal, M., & Sood, S. (2013). Role of curcumin in systemic and oral health: An overview. Journal of natural science, biology, and medicine, 4(1), 3–7. https://doi.org/10.4103/0976-9668.107253
2. Tarasub, N., Junseecha, T., Tarasub, C., & Na Ayutthaya, W. D. (2012). Protective Effects of Curcumin, Vitamin C, or their Combination on Cadmium-Induced Hepatotoxicity. Journal of basic and clinical pharmacy, 3(2), 273–281. https://doi.org/10.4103/0976-0105.103821
3. Shoba, G., Joy, D., Joseph, T., Majeed, M., Rajendran, R., & Srinivas, P. S. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta medica, 64(4), 353–356. https://doi.org/10.1055/s-2006-957450
1.https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(17)30306-5/fulltext#seccestitle10
2. Garcia-Larsen, V., Thawer, N., Charles, D., Cassidy, A., van Zele, T., Thilsing, T., Ahlström, M., Haahtela, T., Keil, T., Matricardi, P. M., Brożek, G., Kowalski, M. L., Makowska, J., Niżankowska-Mogilnicka, E., Rymarczyk, B., Loureiro, C., Todo Bom, A., Bachert, C., Forsberg, B., Janson, C., … Burney, P. G. (2018). Dietary Intake of Flavonoids and Ventilatory Function in European Adults: A GA²LEN Study. Nutrients, 10(1), 95. https://doi.org/10.3390/nu10010095
3. Sadowska, A. M., Verbraecken, J., Darquennes, K., & De Backer, W. A. (2006). Role of N-acetylcysteine in the management of COPD. International journal of chronic obstructive pulmonary disease, 1(4), 425–434. https://doi.org/10.2147/copd.2006.1.4.425
4.https://www.sciencedirect.com/science/article/pii/S095461111630141X
1.https://migraineresearchfoundation.org/about-migraine/migraine-triggers/
2.https://www.healthline.com/health/migraine#causes
3.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335449/#B21
4.https://www.healthline.com/health/migraine-herbal-home-remedies-from-around-the-world#feverfew
5. von Luckner, A., & Riederer, F. (2018). Magnesium in Migraine Prophylaxis-Is There an Evidence-Based Rationale? A Systematic Review. Headache, 58(2), 199–209. https://doi.org/10.1111/head.13217
6. Boehnke, C., Reuter, U., Flach, U., Schuh-Hofer, S., Einhäupl, K. M., & Arnold, G. (2004). High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre. European journal of neurology, 11(7), 475–477. https://doi.org/10.1111/j.1468-1331.2004.00813.x
1.https://acaai.org/allergies/types/hay-fever-rhinitis
2.What Is Quercetin? Benefits, Foods, Dosage, and Side Effects (healthline.com)
3. Ouwehand, Arthur, “Antiallergic effects of probiotics,” Journal of Nutrition, Mar 2007
4. Roschek, B., Jr, Fink, R. C., McMichael, M., & Alberte, R. S. (2009). Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis. Phytotherapy research : PTR, 23(7), 920–926. https://doi.org/10.1002/ptr.2763
2. Sategna-Guidetti, C., Bruno, M., Mazza, E., Carlino, A., Predebon, S., Tagliabue, M., & Brossa, C. (1998). Autoimmune thyroid diseases and coeliac disease. European journal of gastroenterology & hepatology, 10(11), 927–931. https://doi.org/10.1097/00042737-199811000-00005
3. Mainardi, E., Montanelli, A., Dotti, M., Nano, R., & Moscato, G. (2002). Thyroid-related autoantibodies and celiac disease: a role for a gluten-free diet?. Journal of clinical gastroenterology, 35(3), 245–248. https://doi.org/10.1097/00004836-200209000-00009
Food, Recipes and Macronutrients
1. Hammons, Amber & Fiese, Barbara. (2011). Is Frequency of Shared Family Meals Related to the Nutritional Health of Children and Adolescents?. Pediatrics. 127. e1565-74. 10.1542/peds.2010- 1440.
2. Bekelman, T. A., Bellows, L. L., Clark, L., Thompson, D. A., Kemper, G., McCloskey, M. L., & Johnson, S. L. (2019). An Ecocultural Perspective on Eating-Related Routines Among Low- Income Families With Preschool-Aged Children. Qualitative health research, 29(9), 1345–1357. https://doi.org/10.1177/1049732318814540
3. Martin-Biggers, J., Spaccarotella, K., Berhaupt-Glickstein, A., Hongu, N., Worobey, J., & Byrd- Bredbenner, C. (2014). Come and get it! A discussion of family mealtime literature and factors affecting obesity risk. Advances in nutrition (Bethesda, Md.), 5(3), 235–247. https://doi.org/10.3945/an.113.005116
4. Fulkerson, J. A., Kubik, M. Y., Story, M., Lytle, L., & Arcan, C. (2009). Are there nutritional and other benefits associated with family meals among at-risk youth?. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 45(4), 389–395. https://doi.org/10.1016/j.jadohealth.2009.02.011
1. Lebwohl B, Sanders DS, Green PHR. Coeliac disease. Lancet. 2018 Jan 6;391(10115):70-81. doi: 10.1016/S0140-6736(17)31796-8. Epub 2017 Jul 28. PMID: 28760445.
2. NIH Autoimmune Diseases Coordinating Committee: Autoimmune Diseases Research Plan, March 2005. https://www.niaid.nih.gov/sites/default/files/adccfinal.pdf (Last accessed October 10, 2017)
3. Lerner A, Shoenfeld Y, Matthias T. Adverse effects of gluten ingestion and advantages of gluten withdrawal in nonceliac autoimmune disease. Nutr Rev. 2017 Dec 1;75(12):1046-1058. doi: 10.1093/nutrit/nux054. PMID: 29202198.
4.https://www.beyondceliac.org/celiac-disease/non-celiac-gluten-sensitivity/
1.https://my.clevelandclinic.org/health/treatments/9013-dehydration
2.https://www.mayoclinic.org/diseases-conditions/dehydration/symptoms-causes/syc-20354086
3. Tucker KL, Morita K, Qiao N, Hannan MT, Cupples LA, Kiel DP. Colas, but not other carbonated beverages, are associated with low bone mineral density in older women: The Framingham Osteoporosis Study. Am J Clin Nutr. 2006 Oct;84(4):936-42. doi: 10.1093/ajcn/84.4.936. PMID: 17023723.
4.https://jandonline.org/article/S2212-2672(21)00103-9/fulltext
5. Masento, N., Golightly, M., Field, D., Butler, L., & Van Reekum, C. (2014). Effects of hydration status on cognitive performance and mood. British Journal of Nutrition, 111(10), 1841-1852. doi:10.1017/S0007114513004455 https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/effects-of-hydration-status-on-cognitive-performance-and-mood/1210B6BE585E03C71A299C52B51B22F7
1. Van de walle, G. (2018) 9 Important Functions of Protein in Your Body, Healthline.com.
2. Dietary Guidelines for Americans, 2020-2025, U.S. Department of Agriculture (2020) pg. 146.
3. How Much Protein Do You Need Everyday, Harvard Health Publishing, 2015.
4. Evans, W. (2013) Protein Nutrition, Exercise, and Ageing, Journal of the American College of Nutrition.
5. Chernoff, R. (2013) Protein and Older Adults, Journal of the American College of Nutrition.
6. Kresser, C. (2019)How to Calculate Macronutrient Ratios That Work for You, Chriskresser.com.
7. Protein in diet, MedlinePlus, 2019.
1.https://www.ucsfhealth.org/education/increasing-fiber-intake
2.https://www.hsph.harvard.edu/nutritionsource/carbohydrates/fiber/
3.https://my.clevelandclinic.org/health/articles/14400-improving-your-health-with-fiber
4.https://www.bmj.com/content/361/bmj.k2179
6.https://www.ucsfhealth.org/education/increasing-fiber-intake
7.https://www.healthline.com/nutrition/foods-high-in-soluble-fiber
8.https://www.healthline.com/health/digestive-health/whats-the-best-fiber-supplement#psyllium
1. Lodish H, Berk A, Zipursky SL, et al. Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Section 22.3, Collagen: The Fibrous Proteins of the Matrix. Available from: https://www.ncbi.nlm.nih.gov/books/NBK21582/
2. Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47–55. https://doi.org/10.1159/000351376
3. Bello, A. E., & Oesser, S. (2006). Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature. Current medical research and opinion, 22(11), 2221–2232. https://doi.org/10.1185/030079906X148373
4. Dar, Q. A., Schott, E. M., Catheline, S. E., Maynard, R. D., Liu, Z., Kamal, F., Farnsworth, C. W., Ketz, J. P., Mooney, R. A., Hilton, M. J., Jonason, J. H., Prawitt, J., & Zuscik, M. J. (2017). Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. PloS one, 12(4), e0174705. https://doi.org/10.1371/journal.pone.0174705
5. Lopez, et al. Evaluation of the Effects of BioCell Collagen, a Novel Cartilage Extract, on Connective Tissue Support and Functional Recovery From Exercise. Integr Med. 2015 Jun;14(3):30-8.
6. Danby F. W. (2010). Nutrition and aging skin: sugar and glycation. Clinics in dermatology, 28(4), 409–411. https://doi.org/10.1016/j.clindermatol.2010.03.018
7. DePhillipo, N. N., Aman, Z. S., Kennedy, M. I., Begley, J. P., Moatshe, G., & LaPrade, R. F. (2018). Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. Orthopaedic journal of sports medicine, 6(10), 2325967118804544. https://doi.org/10.1177/2325967118804544
8. Harris, E. D., Rayton, J. K., Balthrop, J. E., DiSilvestro, R. A., & Garcia-de-Quevedo, M. (1980). Copper and the synthesis of elastin and collagen. Ciba Foundation symposium, 79, 163–182. https://doi.org/10.1002/9780470720622.ch9
9. Karna, E., Szoka, L., Huynh, T., & Palka, J. A. (2020). Proline-dependent regulation of collagen metabolism. Cellular and molecular life sciences : CMLS, 77(10), 1911–1918. https://doi.org/10.1007/s00018-019-03363-3
10. de Paz-Lugo, P., Lupiáñez, J. A., & Meléndez-Hevia, E. (2018). High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis. Amino acids, 50(10), 1357–1365. https://doi.org/10.1007/s00726-018-2611-x
1. Rimando, A. M., & Perkins-Veazie, P. M. (2005). Determination of citrulline in watermelon rind. Journal of chromatography. A, 1078(1-2), 196–200. https://doi.org/10.1016/j.chroma.2005.05.009
2. Skrovankova, S., Sumczynski, D., Mlcek, J., Jurikova, T., & Sochor, J. (2015). Bioactive Compounds and Antioxidant Activity in Different Types of Berries. International journal of molecular sciences, 16(10), 24673–24706. https://doi.org/10.3390/ijms161024673
3. Delcourt, C., Carrière, I., Delage, M., Barberger-Gateau, P., Schalch, W., & POLA Study Group (2006). Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA Study. Investigative ophthalmology & visual science, 47(6), 2329–2335. https://doi.org/10.1167/iovs.05-1235
4. Viuda-Martos, M., Sanchez-Zapata, E., Sayas-Barberá, E., Sendra, E., Pérez-Álvarez, J. A., & Fernández-López, J. (2014). Tomato and tomato byproducts. Human health benefits of lycopene and its application to meat products: a review. Critical reviews in food science and nutrition, 54(8), 1032–1049. https://doi.org/10.1080/10408398.2011.623799
5. Macfarlane, S., Macfarlane, G. T., & Cummings, J. H. (2006). Review article: prebiotics in the gastrointestinal tract. Alimentary pharmacology & therapeutics, 24(5), 701–714. https://doi.org/10.1111/j.1365-2036.2006.03042.x
1.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442131/
2.https://microbeformulas.com/blogs/microbe-formulas/phytochemicals-101-types-sources-and-benefits
3.https://www.health.harvard.edu/heart-health/vegetable-of-the-month-red-cabbage
4.https://www.seasonalfoodguide.org/
5.https://www.hsph.harvard.edu/nutritionsource/food-features
6.https://draxe.com/nutrition/bell-pepper-nutrition/
1. Ballantyne, S. Why Vegetable Oils are Bad. The Paleo Mom. https://www.thepaleomom.com/vegetable-oils-bad/ Published July 20, 2107. Accessed June 1, 2021.
1. Liao, L. Y., He, Y. F., Li, L., Meng, H., Dong, Y. M., Yi, F., & Xiao, P. G. (2018). A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide. Chinese medicine, 13, 57. https://doi.org/10.1186/s13020-018-0214-9
2. Wachtel-Galor S, Yuen J, Buswell JA, et al. Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92757/
3. Ko, S. K., Jin, M., & Pyo, M. Y. (2011). Inonotus obliquus extracts suppress antigen-specific IgE production through the modulation of Th1/Th2 cytokines in ovalbumin-sensitized mice. Journal of ethnopharmacology, 137(3), 1077–1082. https://doi.org/10.1016/j.jep.2011.07.024
4. Mishra, S. K., Kang, J. H., Kim, D. K., Oh, S. H., & Kim, M. K. (2012). Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis in mice. Journal of ethnopharmacology, 143(2), 524–532. https://doi.org/10.1016/j.jep.2012.07.008
5. Lai P.L., Naidu M., Sabaratnam V., Wong K.H., David R.P., Kuppusamy U.R., Abdullah N., Malek S.N. “Neurotrophic properties of the Lion’s mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia.” International Journal of Medicinal Mushrooms. 2013;15(6):539-54.
6. Mori, K., Obara, Y., Moriya, T., Inatomi, S., & Nakahata, N. (2011). Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice. Biomedical research (Tokyo, Japan), 32(1), 67–72. https://doi.org/10.2220/biomedres.32.67
7. Katie R. Hirsch, Abbie E. Smith-Ryan, Erica J. Roelofs, Eric T. Trexler & Meredith G. Mock (2017) Cordyceps militaris Improves Tolerance to High-Intensity Exercise After Acute and Chronic Supplementation, Journal of Dietary Supplements, 14:1, 42-53, DOI: 10.1080/19390211.2016.1203386
8. Lo, H. C., Tu, S. T., Lin, K. C., & Lin, S. C. (2004). The anti-hyperglycemic activity of the fruiting body of Cordyceps in diabetic rats induced by nicotinamide and streptozotocin. Life sciences, 74(23), 2897–2908. https://doi.org/10.1016/j.lfs.2003.11.003
9. Blagodatski, A., Yatsunskaya, M., Mikhailova, V., Tiasto, V., Kagansky, A., & Katanaev, V. L. (2018). Medicinal mushrooms as an attractive new source of natural compounds for future cancer therapy. Oncotarget, 9(49), 29259–29274. https://doi.org/10.18632/oncotarget.25660
10. Sekhon, B. K., Sze, D. M., Chan, W. K., Fan, K., Li, G. Q., Moore, D. E., & Roubin, R. H. (2013). PSP activates monocytes in resting human peripheral blood mononuclear cells: immunomodulatory implications for cancer treatment. Food chemistry, 138(4), 2201–2209. https://doi.org/10.1016/j.foodchem.2012.11.009
2.https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/#h2
3. Calder P. C. (2006). n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. The American journal of clinical nutrition, 83(6 Suppl), 1505S–1519S. https://doi.org/10.1093/ajcn/83.6.1505S
4. McNamara R. K. (2016). Role of Omega-3 Fatty Acids in the Etiology, Treatment, and Prevention of Depression: Current Status and Future Directions. Journal of nutrition & intermediary metabolism, 5, 96–106. https://doi.org/10.1016/j.jnim.2016.04.004
Lifestyle
1. Eugene, A. R., & Masiak, J. (2015). The Neuroprotective Aspects of Sleep. MEDtube science, 3(1), 35–40.
3. Zeng, Y., Yang, J., Du, J., Pu, X., Yang, X., Yang, S., & Yang, T. (2014). Strategies of Functional Foods Promote Sleep in Human Being. Current signal transduction therapy, 9(3), 148–155. https://doi.org/10.2174/1574362410666150205165504
1. Howatson, G., Bell, P. G., Tallent, J., Middleton, B., McHugh, M. P., & Ellis, J. (2012). Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality. European journal of nutrition, 51(8), 909–916. https://doi.org/10.1007/s00394-011-0263-7
2. Coelho Rabello Lima, L., Oliveira Assumpção, C., Prestes, J., & Sérgio Denadai, B. (2015). CONSUMPTION OF CHERRIES AS A STRATEGY TO ATTENUATE EXERCISE-INDUCED MUSCLE DAMAGE AND INFLAMMATION IN HUMANS. Nutricion hospitalaria, 32(5), 1885–1893. https://doi.org/10.3305/nh.2015.32.5.9709
3.https://www.heart.org/en/health-topics/cholesterol/hdl-good-ldl-bad-cholesterol-and-triglycerides
1. Golem DL, Martin-Biggers JT, Koenings MM, Davis KF, Byrd-Bredbenner C. An integrative review of sleep for nutrition professionals. Adv Nutr. 2014 Nov 14;5(6):742-59. doi: 10.3945/an.114.006809. PMID: 25398735; PMCID: PMC4224209.
1. Jenny Nyberg, Maria A. I. Åberg, Linus Schiöler, Michael Nilsson, Anders Wallin, Kjell Torén, H. Georg Kuhn, Cardiovascular and cognitive fitness at age 18 and risk of early-onset dementia, Brain, Volume 137, Issue 5, May 2014, Pages 1514–1523, https://doi.org/10.1093/brain/awu041
2.https://my.clevelandclinic.org/health/articles/21199-lymphatic-system
3. Santos, L., Elliott-Sale, K. J., & Sale, C. (2017). Exercise and bone health across the lifespan. Biogerontology, 18(6), 931–946. https://doi.org/10.1007/s10522-017-9732-6
4. Kline C. E. (2014). The bidirectional relationship between exercise and sleep: Implications for exercise adherence and sleep improvement. American journal of lifestyle medicine, 8(6), 375–379. https://doi.org/10.1177/1559827614544437
5.https://www.cdc.gov/physicalactivity/basics/pa-health/index.htm
1. Davis C. D. (2016). The Gut Microbiome and Its Role in Obesity. Nutrition today, 51(4), 167–174. https://doi.org/10.1097/NT.0000000000000167
2. Marik P. E. (2020). Vitamin C: an essential "stress hormone" during sepsis. Journal of thoracic disease, 12(Suppl 1), S84–S88. https://doi.org/10.21037/jtd.2019.12.64
3. Jacka, F. N., Overland, S., Stewart, R., Tell, G. S., Bjelland, I., & Mykletun, A. (2009). Association between magnesium intake and depression and anxiety in community-dwelling adults: the Hordaland Health Study. The Australian and New Zealand journal of psychiatry, 43(1), 45–52. https://doi.org/10.1080/00048670802534408
4. Young, L. M., Pipingas, A., White, D. J., Gauci, S., & Scholey, A. (2019). A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and 'At-Risk' Individuals. Nutrients, 11(9), 2232. https://doi.org/10.3390/nu11092232
5.https://www.sciencedirect.com/science/article/pii/S2589936819300167
6. Jackson, E., Shoemaker, R., Larian, N., & Cassis, L. (2017). Adipose Tissue as a Site of Toxin Accumulation. Comprehensive Physiology, 7(4), 1085–1135. https://doi.org/10.1002/cphy.c160038
1. Bates GW, Bates SR, Whitworth NS. Reproductive failure in women who practice weight control. Fertility and Sterility. 1982 Mar;37(3):373-378.
2. Cromer B. A. (2008). Menstrual cycle and bone health in adolescents. Annals of the New York Academy of Sciences, 1135, 196–203. https://doi.org/10.1196/annals.1429.032
3. Derous, D., Mitchell, S. E., Green, C. L., Chen, L., Han, J. D., Wang, Y., Promislow, D. E., Lusseau, D., Speakman, J. R., & Douglas, A. (2016). The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways. Aging, 8(4), 642–663. https://doi.org/10.18632/aging.100895
4. Karklin, A., Driver, H. S., & Buffenstein, R. (1994). Restricted energy intake affects nocturnal body temperature and sleep patterns. The American journal of clinical nutrition, 59(2), 346–349. https://doi.org/10.1093/ajcn/59.2.346
1. Johnson JB, Summer W, Cutler RG, et al. Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma [published correction appears in Free Radic Biol Med. 2007 Nov 1;43(9):1348. Tellejohan, Richard [corrected to Telljohann, Richard]. Free Radic Biol Med. 2007;42(5):665-674 doi:10.1016/j.freeradbiomed.2006.12.005
2. Shin, B. K., Kang, S., Kim, D. S., & Park, S. (2018). Intermittent fasting protects against the deterioration of cognitive function, energy metabolism and dyslipidemia in Alzheimer's disease-induced estrogen deficient rats. Experimental biology and medicine (Maywood, N.J.), 243(4), 334–343. https://doi.org/10.1177/1535370217751610