SAMe  Curated Wellness
SAMe  Curated Wellness
SAMe  Curated Wellness
Regular price $34.19 Sale price$28.04 Save $6.15
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• Key factor in several key biological pathways, including methylation reactions, glutathione formation and glutathione-s-transferase activity*
• Complexed with disulfate tosylate, a well-tolerated, stable and clinically tested form
• Enteric coating protects SAMe degradation from gastric acid, allowing for significantly improved intestinal absorption*
• 200 mg SAMe per tablet, allows for flexible dose titration
• Sourced from the highest quality Italian Isoactive SAMe available on the market
• Isoactive SAMe uses a natural fermentation process that yields 40% higher active ingredients over synthetic variations
• Suitable for vegetarians/vegans


Serving Size: 1 Tablet
Servings Per Container: 30

  Amount Per Serving % of Daily Value
SAMe S-Adenosyl-L-Methionine (from 400 mg SAMe Tosylate Disulfate) 200 mg

Other Ingredients:
Microcrystalline cellulose, mannitol, enteric coating (methacrylic acid copolymer,triethyl citrate, glyceryl palmitostearate, silica, titanium dioxide, medium chain triglycerides, yellow iron oxide), glyceryl behenate, magnesium stearate (vegetable grade), silica, sodium starch glycolate


Wheat Free, Dairy/ Milk Free, Gluten Free, Vegetarian, Soy Free, Yeast Free, Sugar Free, Starch Free, Preservative Free, Salt Free, Vegan, Corn Free, Free of Artificial Colors/Flavors, Egg Free, Shellfish Free, Non-GMO, Fish Free, Tree Nut Free


Take on an empty stomach:
For mood balance: 1–4 tablets 2 times per day or as directed by a health care professional.
For joint support: 1–3 tablets 2 times per day or as directed by a health care professional. Do not exceed a total of 8 tablets per day. SAMe must be taken for a minimum of 2 weeks, at which time effects should be observed.




If you are taking anti-depressant medications, consult a health care professional prior to taking SAMe in place of or in addition to those medications. Not recommended for use in children. Do not take at night as SAMe may cause anxiety, restlessness, insomnia. People with bipolar disorder or (manic-depressive illness) should not use SAMe unless under medical supervision. Possible side effects are: mild gastrointestinal upsets (such as stomach pain, nausea, diarrhea, flatulence), anxiety, hyperactive muscle movement, insomnia and hypomania. When these side effects occur, they often diminish with time or resolve with lower doses or cessation of use. There are no documented cases of allergies to SAMe. Consult your healthcare professional prior to use if you are pregnant, trying to become pregnant, breastfeeding, taking medication, have a medical condition, or anticipate surgery. Keep out of reach of children.
Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Contains 200 mg of high quality SAMe, produced using a natural fermentation process that yields higher active ingredients over synthetic variations. Enteric coated to ensure a biologically active product.

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