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Curcumin Bio combines our "Heat-Solubilized" curcumin with phosphatidylcholine, a major constituent of cell membranes and is more commonly found in the exoplasmic or outer leaflet of a cell membrane. Curcumin is thought to be transported between membranes within the cell by phosphatidylcholine transfer protein (PCTP).* Phosphatidylcholine helps facilitate curcumin into the cells where it can have the most benefit rather than only being in blood plasma. Curcumin, a polyphenol natural compound extracted from the plant Curcuma longa L., is commonly used as spice in India and Southeast Asia and traditionally used for its proven benefit in inflammatory disorders. *